Bone Disease in Chronic Kidney Disease (CKD): General View and New Classification.
Visão Geral da Doença Óssea na Doença Renal Crônica (DRC) e Nova Classificação
Chronic kidney disease (CKD) is accompanied by disturbances in calcium, phosphate, calcitriol, and parathyroid hormone (PTH) homeostasis that play an important role in the pathophysiology of renal bone disease and are an important cause of morbidity. These disturbances have traditionally been termed renal osteodystrophy and classified based on bone biopsy. "Kidney Disease: Improving Global Outcomes" (KDIGO) recommended that the term renal osteodystrophy should be used exclusively to define alterations in bone histology associated with CKD, and proposed a new term to describe the syndrome of biochemical, bone and extra-skeletal calcification abnormalities that occur in these patients. The new term is CKD-MBD (CKD-Mineral and Bone Disorder)
Descriptors: Renal osteodystrophy. Mineral and bone disorder of chronic kidney disease. CKD-MBD. Classification.